产品货号:
GS4532
中文名称:
重组小鼠SDF-1β/CXCL12β
英文名称:
Recombinant Murine Stromal-Cell Derived Factor-1 beta/CXCL12b
产品规格:
2μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately 8.5kDa,a single non-glycosylated polypeptide chain containing 72 amino acids.
储存条件:冷冻(-20℃)
概述
CXCL12 also known as SDF-1 is belonging to the CXC chemokine family.Murine CXCL12 is expressed as two isoforms that differ only in the C-terminal tail.Both SDF-1 isoforms undergo proteolytic processing of the first two N-terminal amino acids.In all SDF-1 isoforms,SDF-1β is the canonical sequence.It has the complete amino acids in the C-terminal tail.On the cell surface,the receptor for this chemokine is CXCR4 and syndecan4.CXCL12 is strongly chemotactic for T-lymphocytes,monocytes,but not neutrophils.SDF-1 is highly conserved between species,murine CXCL12β shares approximately 92%amino acid sequence identity with human CXCL12β.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索:重组小鼠SDF-1β/CXCL12β,SDF-1β/CXCL12β, Murine
储存条件:冷冻(-20℃)
概述
CXCL12 also known as SDF-1 is belonging to the CXC chemokine family.Murine CXCL12 is expressed as two isoforms that differ only in the C-terminal tail.Both SDF-1 isoforms undergo proteolytic processing of the first two N-terminal amino acids.In all SDF-1 isoforms,SDF-1β is the canonical sequence.It has the complete amino acids in the C-terminal tail.On the cell surface,the receptor for this chemokine is CXCR4 and syndecan4.CXCL12 is strongly chemotactic for T-lymphocytes,monocytes,but not neutrophils.SDF-1 is highly conserved between species,murine CXCL12β shares approximately 92%amino acid sequence identity with human CXCL12β.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
纯度 | >97%by SDS-PAGE and HPLC analyses. |
来源 | Escherichia coli. |
生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 50-100ng/ml. |
成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150 mM NaCl. |
内毒素 | Less than 1 EU/μg of rMuSDF-1β/CXCL12βas determined by LAL method. |
复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions. |
氨基酸序列 | KPVSLSYRCP CRFFESHIAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNKRL KM |
相关搜索:重组小鼠SDF-1β/CXCL12β,SDF-1β/CXCL12β, Murine